The molecular genetics of cellular oncogenes.

DEFINITIONS OF CELLULAR ONCOGENES ................................................ c-onc’s: The Proto-Oncogenic Progenitors of Retroviral Oncogenes . . . . . . . . . . . . . . . . . . . Identification of Cellular Oncogenes by Functional Tests for Dominant Mutations Using Genetic Rearrangements to Identify Oncogenes.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Proviral insertions can activate expression of cellular proto-oncogenes . . . . . . . . . . . Oncogenes at translocation breakpoints.. . . , , . . . . , . . . . . . . . . . . . . . . . . Oncogenes in amplified DNA . , , ... . . ..... , , ... .... , .. .. . .... . .. .. _.. .._. .... . .. .. .. .. . ... MOLECULAR PROFILES OF ACTIVATED ONCOGENES.. . . . . . . . . Base Substitutions in Mutant ras Alleles ................................ Insertionally Mutated c-myc Loci.. . . . . . . . . . . . , . . , . . . . , , . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ~